2021 Buffalo Bills schedule

Season statistics

Offense Defense
Record Playoff record Total yards Pass yards Rush yards Turnovers First downs Total yards Pass yards Rush yards Turnovers First downs
11-6-0 1-1 8348 5587 2761 24 514 6352 3904 2448 35 386
Scroll the table for more season statistics.

The Buffalo Bills' sixty-second season was in 2021, and it was the fifth season Sean McDermott served as the head coach of the team. The Bills played their home games at Highmark Stadium. They finished the year 11-6-0 in the regular season, en route to winning the AFC East, and 1-1 in the playoffs, eventually losing to the Kansas City Chiefs 42-36.


Week Opponent Score Notes
Preaseason Week 1 @ Detroit Lions 16-15
Preaseason Week 2 @ Chicago Bears 41-15
Preaseason Week 3 Green Bay Packers 19-0
Preaseason Week 4 @ Los Angeles Rams 2021-09-08
Week 1 Pittsburgh Steelers 16-23
Week 2 @ Miami Dolphins 35-0
Week 3 Washington Football Team 43-21
Week 4 Bye Week
Week 4 Houston Texans 40-0
Week 5 @ Kansas City Chiefs 38-20
Week 6 @ Tennessee Titans 31-34
Week 7 Bye Week
Week 8 Miami Dolphins 26-11
Week 9 @ Jacksonville Jaguars 6-9
Week 10 @ New York Jets 45-17
Week 11 Indianapolis Colts 15-41
Week 12 @ New Orleans Saints 31-6
Week 13 New England Patriots 10-14
Week 14 @ Tampa Bay Buccaneers 27-33
Week 15 Carolina Panthers 31-14
Week 16 @ New England Patriots 33-21
Week 17 Atlanta Falcons 29-15
Week 18 New York Jets 27-10


Week Opponent Score Notes
Wild Card Round New England Patriots 47-17
Divisional Round @ Kansas City Chiefs 36-42

2021 Buffalo Bills Coaching Staff

Head Coach: Sean McDermott Assistant Head Coach: Leslie Frazier Offensive Coordinator: Brian Daboll Defensive Coordinator: Leslie Frazier Special Teams Coordinator: Heath Farwell Offensive Pass Game Coordinator: Ken Dorsey Quarterbacks Coach: Ken Dorsey Wide Receivers Coach: Chad Hall Offensive Line Coach: Bobby Johnson Running Backs Coach: Kelly Skipper Tight Ends Coach: Rob Boras Assistant Quarterbacks Coach: Shea Tierney Assistant Wide Receivers Coach: Marc Lubick Assistant Offensive Line Coach: Terry Heffernan, Ryan Wendell Game Management: Marc Lubick Defensive Line Coach: Eric Washington Linebackers Coach: Bob Babich Safeties Coach: Bobby Babich Defensive Backs Coach: John Butler Assistant Defensive Line Coach: Jacques Cesaire Nickels Coach: Jim Salgado Assistant Special Teams Coach: Matthew Smiley Assistant to the Head Coach: Matt Worswick Coaching Assistant: Leonard Johnson Head Strength and Conditioning Coach: Eric Ciano Assistant Strength and Conditioning Coach: Hal Luther, Will Greenberg Strength and Conditioning Assistant Coach: Jason Oszvart, Nick Lacy Player Services Coordinator: Laura Young General Manager: Brandon Beane