2021 Buffalo Bills schedule
Season statistics
| Offense | Defense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Record | Playoff record | Total yards | Pass yards | Rush yards | Turnovers | First downs | Total yards | Pass yards | Rush yards | Turnovers | First downs |
| 11-6-0 | 1-1 | 8348 | 5587 | 2761 | 24 | 514 | 6352 | 3904 | 2448 | 35 | 386 |
The Buffalo Bills' sixty-second season was in 2021, and it was the fifth season Sean McDermott served as the head coach of the team. The Bills played their home games at Highmark Stadium. They finished the year 11-6-0 in the regular season, en route to winning the AFC East, and 1-1 in the playoffs, eventually losing to the Kansas City Chiefs 42-36.
Games
| Week | Opponent | Score | Notes | |
|---|---|---|---|---|
| Preaseason Week 1 | @ | Detroit Lions | 16-15 | |
| Preaseason Week 2 | @ | Chicago Bears | 41-15 | |
| Preaseason Week 3 | Green Bay Packers | 19-0 | ||
| Preaseason Week 4 | @ | Los Angeles Rams | 2021-09-08 | |
| Week 1 | Pittsburgh Steelers | 16-23 | ||
| Week 2 | @ | Miami Dolphins | 35-0 | |
| Week 3 | Washington Football Team | 43-21 | ||
| Week 4 | Bye Week | |||
| Week 4 | Houston Texans | 40-0 | ||
| Week 5 | @ | Kansas City Chiefs | 38-20 | |
| Week 6 | @ | Tennessee Titans | 31-34 | |
| Week 7 | Bye Week | |||
| Week 8 | Miami Dolphins | 26-11 | ||
| Week 9 | @ | Jacksonville Jaguars | 6-9 | |
| Week 10 | @ | New York Jets | 45-17 | |
| Week 11 | Indianapolis Colts | 15-41 | ||
| Week 12 | @ | New Orleans Saints | 31-6 | |
| Week 13 | New England Patriots | 10-14 | ||
| Week 14 | @ | Tampa Bay Buccaneers | 27-33 | |
| Week 15 | Carolina Panthers | 31-14 | ||
| Week 16 | @ | New England Patriots | 33-21 | |
| Week 17 | Atlanta Falcons | 29-15 | ||
| Week 18 | New York Jets | 27-10 |
Playoffs
| Week | Opponent | Score | Notes | |
|---|---|---|---|---|
| Wild Card Round | New England Patriots | 47-17 | ||
| Divisional Round | @ | Kansas City Chiefs | 36-42 |
2021 Buffalo Bills Coaching Staff
Head Coach: Sean McDermott Assistant Head Coach: Leslie Frazier Offensive Coordinator: Brian Daboll Defensive Coordinator: Leslie Frazier Special Teams Coordinator: Heath Farwell Passing Game Coordinator: Ken Dorsey Quarterbacks Coach: Ken Dorsey Assistant Quarterbacks Coach: Shea Tierney Wide Receivers Coach: Chad Hall Assistant Wide Receivers Coach: Marc Lubick Offensive Line Coach: Bobby Johnson Assistant Offensive Line Coach: Terry Heffernan, Ryan Wendell Running Backs Coach: Kelly Skipper Tight Ends Coach: Rob Boras Defensive Line Coach: Eric Washington Assistant Defensive Line Coach: Jacques Cesaire Linebackers Coach: Bob Babich Safeties Coach: Bobby Babich Defensive Backs Coach: John Butler Nickels Coach: Jim Salgado Assistant Special Teams Coach: Matthew Smiley Assistant to the Head Coach: Matt Worswick Coaching Assistant: Leonard Johnson Game Management: Marc Lubick Head Strength and Conditioning Coach: Eric Ciano Assistant Strength and Conditioning Coach: Hal Luther, Will Greenberg Strength and Conditioning Assistant Coach: Jason Oszvart General Manager: Brandon Beane Director of Pro Personnel: Malik Boyd