2021 San Francisco 49ers schedule

Season statistics

Offense Defense
Record Playoff record Total yards Pass yards Rush yards Turnovers First downs Total yards Pass yards Rush yards Turnovers First downs
10-7-0 2-1 8261 5205 3056 32 469 6868 4704 2164 26 421
Scroll the table for more season statistics.

The San Francisco 49ers' seventy-sixth season was in 2021, and it was the fifth season Kyle Shanahan served as the head coach of the team. The 49ers played their home games at Levi's Stadium. They finished the year 10-7-0 in the regular season and 2-1 in the playoffs, eventually losing to the Los Angeles Rams 20-17.


Week Opponent Score Notes
Preaseason Week 1 Kansas City Chiefs 16-19
Preaseason Week 2 @ Los Angeles Chargers 15-10
Preaseason Week 3 Las Vegas Raiders 34-10
Preaseason Week 4 @ Chicago Bears 2021-09-11
Week 1 @ Detroit Lions 41-33
Week 2 @ Philadelphia Eagles 17-11
Week 3 Green Bay Packers 28-30
Week 4 Bye Week
Week 4 Seattle Seahawks 21-28
Week 5 @ Arizona Cardinals 10-17
Week 6 Bye Week
Week 7 Indianapolis Colts 18-30
Week 8 @ Chicago Bears 33-22
Week 9 Arizona Cardinals 17-31
Week 10 Los Angeles Rams 31-10
Week 11 @ Jacksonville Jaguars 30-10
Week 12 Minnesota Vikings 34-26
Week 13 @ Seattle Seahawks 23-30
Week 14 @ Cincinnati Bengals 26-23
Week 15 Atlanta Falcons 31-13
Week 16 @ Tennessee Titans 17-20
Week 17 Houston Texans 23-7
Week 18 @ Los Angeles Rams 27-24


Week Opponent Score Notes
Wild Card Round @ Dallas Cowboys 23-17
Divisional Round @ Green Bay Packers 13-10
Conference Championship @ Los Angeles Rams 17-20

2021 San Francisco 49ers Coaching Staff

Head Coach: Kyle Shanahan Assistant Head Coach: Jon Embree Offensive Coordinator: Mike McDaniel Defensive Coordinator: DeMeco Ryans Special Teams Coordinator: Richard Hightower Quarterbacks Coach: Rich Scangarello Wide Receivers Coach: Wes Welker Offensive Line Coach: Chris Foerster Running Backs Coach: Bobby Turner Tight Ends Coach: Jon Embree Assistant Offensive Line Coach: Butch Barry, Zach Yenser Offensive Passing Game Specialist: Bobby Slowik Run Game Specialist: James Bettcher Offensive Quality Control Coach: Brian Fleury, Leonard Hankerson Defensive Line Coach: Kris Kocurek Linebackers Coach: Johnny Holland Safeties Coach: Daniel Bullocks Secondary Coach: Cory Undlin Senior Defensive Assistant Coach: James Bettcher Assistant Defensive Line Coach: Darryl Tapp Defensive Pass Game Specialist: Cory Undlin Defensive Quality Control Coach: Andrew Hayes-Stoker, Klay Kubiak Assistant Special Teams Coach: Matthew Harper Special Teams Quality Control Coach: August Mangin Head Strength and Conditioning Coach: Dustin Perry Assistant Strength and Conditioning Coach: Shea Thompson Director of Performance Monitoring: Shea Thompson Director of Alumni Relations: Guy McIntyre General Manager: John Lynch Manager of Football Research and Development: Demitrius Washington Administrative Assistant to the Head Coach: Nick Kray Assistant to the Coaching Staff: Patrick Hagedorn