2021 San Francisco 49ers schedule

Season statistics

Offense Defense
Record Playoff record Total yards Pass yards Rush yards Turnovers First downs Total yards Pass yards Rush yards Turnovers First downs
0-0-0 0-0 0 0 0 0 0 0 0 0 0 0
Scroll the table for more season statistics.

2021 is the seventy-sixth season for the San Francisco 49ers and the fifth season for Kyle Shanahan as the head coach of the 49ers. They open their season on Sunday, September 12, 2021 versus the Detroit Lions.


Week Opponent Score Notes
Week 1 @ Detroit Lions 2021-09-12
Week 2 @ Philadelphia Eagles 2021-09-19
Week 3 Green Bay Packers 2021-09-26
Week 4 Seattle Seahawks 2021-10-03
Week 5 @ Arizona Cardinals 2021-10-10
Week 7 Indianapolis Colts 2021-10-24
Week 8 @ Chicago Bears 2021-10-31
Week 9 Arizona Cardinals 2021-11-07
Week 10 Los Angeles Rams 2021-11-15
Week 11 @ Jacksonville Jaguars 2021-11-21
Week 12 Minnesota Vikings 2021-11-28
Week 13 @ Seattle Seahawks 2021-12-05
Week 14 @ Cincinnati Bengals 2021-12-12
Week 15 Atlanta Falcons 2021-12-19
Week 16 @ Tennessee Titans 2021-12-23
Week 17 Houston Texans 2022-01-02
Week 18 @ Los Angeles Rams 2022-01-09


Head Coach: Kyle Shanahan Assistant Head Coach: Jon William Embree Offensive Coordinator: Mike McDaniel Defensive Coordinator: DeMeco Ryans Quarterbacks Coach: Rich Scangarello Wide Receivers Coach: Wes Welker Offensive Line Coach: Chris Foerster Assistant Offensive Line Coach: Butch Barry, Zach Yenser Running Backs Coach: Bobby Turner Tight Ends Coach: Jon William Embree Defensive Line Coach: Kris Kocurek Assistant Defensive Line Coach: Darryl Tapp Linebackers Coach: Johnny Holland Safeties Coach: Daniel Bullocks Secondary Coach: Cory Undlin Senior Defensive Assistant Coach: James Bettcher Special Teams Coach: Richard Hightower Assistant Special Teams Coach: Matthew Harper Special Teams Quality Control Coach: August Mangin Defensive Quality Control Coach: Andrew Hayes-Stoker, Klay Kubiak Offensive Quality Control Coach: Brian Fleury, Leonard Hankerson Defensive Pass Game Specialist: Cory Undlin Offensive Passing Game Specialist: Bobby Slowik Run Game Specialist: James Bettcher Administrative Assistant to the Head Coach: Nick Kray Assistant to the Coaching Staff: Patrick Hagedorn